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The Nobel Prize for Medicine for the discovery of AIDS and the discovery of the link between the papilloma virus and cervical cancer

The Nobel Prize Committee decided to award the 2008 Medicine Prize to the discoverers of two viruses that cause serious diseases in humans, and who went against the mainstream in order to convince the scientific community of their discoveries

The AIDS virus HIV. Illustration from the Nobel Prize website
The AIDS virus HIV. Illustration from the Nobel Prize website

Today, the announcement of Nobel Prize winners for 2008 began in Stockholm, Sweden. The first prize announced is the Nobel Prize for Medicine and Physiology. This year the prize committee decided to give a joint prize to two discoverers of viruses that are making a name for themselves among humans.

Half of the prize amount will be awarded to the German Harald Zur Hausen from the Center for Cancer Research in Heidelberg, Germany, for his discoveries that led to the understanding of the relationship between the papilloma virus and cervical cancer, and the other half will be divided between two French scientists: Francois Bar-Sinoussi from the Division for the Control of Retroviral Infections in the Department of Virology at the Pasteur Institute in Paris and Luc Montang R., from the World Fund for AIDS Research and Prevention in Paris from France who discovered the AIDS virus.

Harald von Hauser went against the dogma that was practiced in his time (the seventies) which did not believe that there was any connection between a virus and cancer. He insisted that the human papillomavirus (HPV) causes cervical cancer, the second most common type of cancer in women. He realized that the HPV DNA may exist in an inactive state in the tumor, and may be detected through a specific search for viral DNA. He discovered that the HPV is actually a heterogeneous family of viruses and only some of them cause cancer. His discovery led to the characterization of the history of HPV infection, an understanding of the mechanism by which HPV acts as a catalyst for the formation of cancer and the development of a preventive vaccine against HPV infection.

Françoise Bar-Sinoussi and Luc Montgier discovered the human immunodeficiency virus (HIV). Virus production was detected in the lymph cells of patients with enlarged lymph nodes in the early stages of the disease, and in the blood of patients in the later stages of the disease. They characterized the retrovirus based on its morphological, biochemical and immunological properties. HIV weakens the immune system due to its enormous replication capacity and the damage it causes to lymphocyte cells. The discovery was a prerequisite for understanding the biology of these diseases and the antiretroviral treatments.

Discovering the relationship between the papilloma virus and cervical cancer

Against the prevailing position during the 16s, Zur HaOzen outlined the way to understanding the role of the human papillomavirus in the development of cervical cancer. He hypothesized that the tumor cells, if they contain an oncogenic virus, should preserve within them viral DNA within the genome. In such a case, it will be possible to discover the cells containing the HPV genome in the viral DNA search inventions. Zur HaOzen advanced the idea for ten years by studying different types of HPV, a study that proved to be difficult due to the work that only one part of the viral DNA was integrated into the host's genome. He found new sequences of the HPV in biopsy samples of cervical cancer patients and thus discovered, among other things, the cancerous virus HPV type 1983. In 4-16 he cloned the virus types 18 and 70 from cervical cancer patients. It turns out that these two types were consistently found in about XNUMX% of the biopsies of cervical cancer lesions from all over the world.

The importance of HPV detection

Cervical cancer caused by the papilloma virus accounts for over 5% of all cancer morbidity in the general population. Human papillomavirus infection is the most common sexually transmitted disease, affecting 50-80% of the population. Of the above known types of HPV, about 40% leave a genetic imprint and 15 of them place the carriers at a high risk of cervical cancer. In addition, HPV sequences have also been found in vulvar cancer, penile cancer (in males), oral cancer and other types of cancer. The human papillomavirus may be detected in 99.7% of women who have cervical cancer, which affects about half a million women a year.

Harald Zur Hauzen demonstrated innovative properties of the HPV that led him to understand the mechanism of increasing cancer incidence and sensitivity factors to the persistence of the virus and the transformation process that the cell undergoes. He made HPV 16 and 18 available to the scientific community. Until now, vaccines have been developed that provide over 95% protection against infection with these dangerous virus types. The vaccines also reduce the need for surgery and the suffering caused by cervical cancer.

19 תגובות

  1. Nowhere in your book is it written to kill Shabbat violators.
    The essence of the Torah is the Ten Commandments, where it is written in the passage not to murder.
    The problem with religions is that there are many currents according to different interpretations of messiahs or just "great in the Torah".
    There are even different prayer houses according to testimony.
    Man chooses to separate himself from the rest according to a superficial definition instead of seeking unity.
    Extremist currents whose religious feeling gives them a feeling of superiority or that they carry out the "will of God" are certainly sometimes and it would be better for the world without them (but who am I to decide..)

  2. Dawn:
    A person is not born a murderer, but if he is brought up according to religion, he learns that homosexuals and sabbath breakers should be murdered.
    This is what the Torah commands him to do.

  3. Really shocking
    But what is even more important is that many of the leaders of the "free" world are members of this group -
    Economic elites, state leaders, "religious" people

  4. The scientist, what can I tell you? "The abominations of the Gentiles and their deeds". People are very disturbed in their minds and I have nothing but to bless that this will not be done in our places. Let me study a page of Gemara at any time and not burn giant statues of owls and run around at night dressed like a member of the Ku Klux Klan. Shocking and thanks for this link.

  5. the science -
    Well, I've also heard of the "Hiros Gamos" and things like that. I don't know how widespread the phenomenon really is and how much it is really related to idolatry these days, as opposed to just an unbridled lust for flesh. I'll just add and say, as much as it's a sexual matter, it's ugly and immoral behavior - but it's not at all commensurate with the degree of seriousness of a sexual act, whether heterosexual or otherwise, which is intended for the ecstasy of a composer to statues, paper dolls, stars and zodiac signs and other types of madness.

  6. Quote" 2. Homosexuality for the sake of worshiping idols (orgies) - an act that does not exist today, but was very common in ancient times.


    There is a group of elitists who hold similar rituals even today.
    Most US presidents belong to it to this day.
    "The Bohemians"

  7. Killing is a personal choice.
    Homosexuality is an innate trait and a wide-ranging phenomenon whose existence cannot be disputed.

    A person is not born a murderer, but there is a chance that he will be born gay.
    Today there are also asexual people who are not really interested in sex
    (I guess there are some in the science system as well...)

  8. Well, homosexuality is a trivial subject to analyze from a halachic point of view, but I can present two general lines of thought regarding it - 1. Homosexuality that stems from human genetics - such people are "raped by the hands of heaven" and cannot avoid their preference that is in their nature and with which they were born. 2. Homosexuality for the worship of idolatry (orgies) - an act that does not exist nowadays, but was very common in ancient times - from a halachic point of view, this is an abominable and disgusting act (like all idolatry). 3. I don't think that the creator of the world "wanted" (in any case, he should not be attributed a "will" in a human sense) to encourage adultery or relationships of this or that kind. The fact is that the world he created is a world that allows us freedom of choice and also a world where we bear responsibility for the results of our choices. It is true that this may sound like a contradiction with my claim about homosexuals being "raped by heaven", but in terms of choice they are no more raped than heterosexuals. It's just that their choice is dictated by their nature, to their own kind.

  9. Dawn:
    So what? He encourages people to commit adultery or have homosexual relations and then orders others to murder them for it?
    Wow - what a goddamn shit!

  10. I don't know who the creator of the world is, but in my opinion, if the phenomenon exists, it is a sign that he wants it.
    Maybe homosexual relationships are meant to reduce reproduction in the population? A kind of breeding dilution mechanism?

  11. I don't know if this is true, but if so - doesn't this mean that the creator of the world wanted to encourage adultery and homosexual relations?

  12. On International AIDS Day, which began today, we will recall the apparent connection, in studies on thousands of subjects, between circumcision and a significant reduction in the chance of contracting AIDS -

    Of course, skeptics can deny this matter or the connection to the infinite wisdom of the Creator of the world to their heart's content. Believers can just quietly smile to themselves.

  13. There is respect
    Of the more important and less important branches of science, this branch contributes to the well-being of the human race in the most prominent way in my opinion. Applause.

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