100 new points on chromosome #7 were found to be associated with genetic disorders * The research relied on the two sequences of the human genome - that of Celera and that of the Free International Group of Scientists
Direct link to this page: https://www.hayadan.org.il/autisomgene.html
Mapping the genetic sequence of the DNA belonging to chromosome 7 sheds light on genes related to autism, some types of leukemia and lymphomas1.
Geneticist Stephen Scherer of the University of Toronto and his colleagues identified the site and found 100 mutations associated with genetic disorders after studying the genetic sequence of 300 new patients and examining 1,750 published articles and studies.
The researchers were able to develop a new database in which a sequence of anomalies is kept, and decide whether the patient's genetic pattern matches that of others. The more the data accumulates in the database that will be open to the public of scientists, the more candidate genes for disorders can be discovered." Sherer said in an interview with the journal Nature.
Some of the mutations found in patients with autism were in the genes responsible for speech and communication. Others were closer to genes that allow neurons to communicate.
The genetics of autism are complicated, warns Beth Rosen-Sheidley of Tufts New England Medical Center in Boston. "A change in one garden is not enough for most families. "Any test for the disease will be complicated to interpret," she said. "It's a kind of swamp. One of the signs of the disease may increase the risk, but by how much?"
In order to produce an accurate map, Sherer's team started with the draft genetic sequence of chromosome #7 published by the private company Celera Genomics 2. They then filled in many of the gaps with data from those published by the International Public Consortium, which also mapped the human genome.
The researchers admitted that the published sequences are not completely complete, but they estimate that it is in reasonable condition. Others believe, however, that there is still a long way to go until completion.
For information in Nature
The human genome scientist
https://www.hayadan.org.il/BuildaGate4/general2/data_card.php?Cat=~~~505935856~~~25&SiteName=hayadan
