Comprehensive coverage

Weizmann Institute

Embryonic stem cells. Image: depositphotos.com

The superpower of a newborn fetus

How can cells be returned to their initial and most powerful state?
An AIRE-ILC3 cell (in green) kisses a TH17 cell (in red) and thus commands it to proliferate (top row). In contrast, it does not bind to other T cells that are not designed to fight candida (bottom line)

The cells that prevent candida from returning

Weizmann Institute of Science scientists have uncovered a mechanism of the immune system that helps fight Candida infections
Spirulina. Illustration: depositphotos.com

Breakfast of champions

When did unicellular algae become so nutritious - and how the change paved the way for an evolutionary leap
XNUMXD structure of an enzyme from the versatile peroxidase family generated through artificial intelligence-based prediction. The yellow dots mark mutations introduced by the algorithm developed in Prof. Fleishman's laboratory, with the aim of increasing the stability of the enzyme

The proteins of the future are already here

A combination of artificial intelligence and protein design algorithms allows for the first time access to a gold mine: millions of natural proteins that can be used in a variety of environmental, medical and industrial applications
In healthy skin tissue samples (left) ScAF cells show thin and elongated "tails" (in green), while in patients with limited scleroderma (center) - and even more so in patients with diffuse scleroderma (right) - there are fewer and fewer ScAF cells, and those that remain gradually lose their Their elongated tails show different expression levels of some proteins (marked in blue and red)

In a new skin: transforming every cell on the way to understanding a rare autoimmune disease

Weizmann Institute of Science scientists in collaboration with Hadassah and Rambam doctors present a new road map for the study of diseases in which there is still much that is hidden on the open
The butterfly hunter from the Jezreel valley dreamed of studying biology, until he came across an old physics book and discovered that natural phenomena can be calculated with mathematical tools. You are here Home > Publications > Milestone > In a nuclear shell Share tags Yigal nuclear thalamiphysics The shell model When the Soviet government closed the schools that taught Hebrew, Prof. Ben-Zion Dinburg (later Dinor, Minister of Education and Culture) arranged immigration licenses ("certificates") for teachers in the hope of bringing them to kibbutzim and moshavim. Thus, four years after the founding of Kfar Yehezkel, the second workers' settlement in the Land of Israel, the Ptolemy (formerly Smilansky) family, who immigrated from Ukraine in 1925, joined its ranks: the parents Moshe and Leah, teachers of Hebrew, their daughter Tahia, about ten years old, and their toddler son, Yigal, less than one year old. On the ship that arrived from Odessa to Jaffa there were two more families of teachers, but they stayed in Tel Aviv, which seemed quite pioneering to them. Yigal grew up in Moshav at the foot of the Gilboa, in the heart of the Jezreel Valley, and studied until the XNUMXth grade at the school in the village that his father ran (one of his students, Azaria Alon, wrote highly of Moshe Ptolemy). The XNUMXth grade was in the Geva group, and Vigal and four other boys walked to the Geva every morning. When it rained and water flowed in the wadi between the settlements, crossing was not possible. Prof. Yigal Ptolemy. Contributed a lot to shaping the image of the Weizmann Institute

in the nuclear envelope

The butterfly hunter from the Jezreel Valley dreamed of studying biology, until he came across an old physics book and discovered that natural phenomena can be calculated with mathematical tools
The beginning of life. Illustration - shutterstock

In the beginning there was soap

What was the first chemical entity that met the basic conditions for life?
An MRI scan of a mouse brain shows with the help of two colors the expression of two different proteins. Weizmann Institute

Through the Tissues: The New Life of MRI Scans

If it were possible, for example, to mark with colors the expression of genes in the cells of the body, vital biological processes that are now hidden from view would unfold before our eyes. The fluorescence revolution makes it possible to illuminate, in the full sense of the word, the activity occurring in the cells, but it does not allow observing the processes occurring in the depths of the body
Mice in a smoking friendly bar. Illustration: depositphotos.com

The smoking gun of the link between smoking cessation and obesity: gut bacteria

Nicotine and other compounds found in cigarettes penetrate the intestine through the bloodstream and change the composition of the intestinal bacteria and their products
Bacteriophages attack bacteria. Illustration: depositphotos.com

The common fight of bacteria and plants against viruses

A defense mechanism discovered in bacteria may make it possible to improve the resistance of agricultural crops to pests
Cancer treatment. Illustration: depositphotos.com

Break the boundaries of immunotherapy

The method that may make the new generation of cancer treatments accessible to more patients
DNA molecule. Image: depositphotos.com

The loom of evolution

A new method makes it possible to locate points of similarity between gene control molecules of different species - from lizards to humans - and thus reveal essential sections that have been preserved throughout evolution
The oxygen revolution left its geochemical record in the iron deposits in the earth's mantle and rocks

The oxygen before the oxygen revolution

By tracing the evolution of proteins, Weizmann Institute of Science scientists have charted the history of oxygen availability on Earth and solved a long-standing scientific puzzle
A black hole emits jets of particles. Image: depositphotos.com

For the first time, a neutrino particle has been detected that came to us from the vicinity of a supermassive black hole

  • 50 תגובות
A group of international researchers, including from the Hebrew University and the Weizmann Institute, discovered the particle that arrived following an emission event that occurred in 2019
A swarm of hexagons is crushed into a passing car. Photo: shutterstock

The humming of the tentacles' inclusions

  • No comments
The tentacles, relatives of the mosquitoes, have a strange wedding custom, they choose their spouse in a huge swarm of tentacles and yet continue to stick together. A new study managed to decipher the phenomenon
As we add ingredients to a fruit smoothie, it will be difficult to put our finger on the contribution of each ingredient to the final result. A fruit salad, on the other hand, allows you to combine flavors without masking the unique contribution of each fruit. Similarly, when checking the average gene expression in a certain tissue (left), it is not possible to distinguish the differences between different cells in the same tissue. Technological developments of recent years make it possible to measure the expression of genes in a tissue at the level of the single cell (right), thus characterizing with unprecedented resolution differences between cells in the same tissue

Each and every cell is stressed: first mapping of the "stress axis" at the individual cell level

From the brain to the adrenal glands - scientists from the Weizmann Institute of Science and the Max Planck Institute have mapped the entire "stress axis" and shown how chronic stress affects and changes these tissues at the individual cell level. The scientists discovered a new subpopulation of endocrine cells involved in regulating the response to chronic stress
Liron Grover and Prof. Ehud Ahisher. with a sensitive eye. Weizmann Institute spokeswoman photo

Eyes closed

Bacteriophage - a virus that attacks bacteria. Illustration: Illustration: depositphotos.com

A mysterious component in bacteria has been discovered as a last line of defense against viral infection

  • 6 תגובות
Besides solving a 36-year-old mystery, Weizmann Institute of Science scientists have identified thousands of types of these components, which may be used in gene editing
cancer cell Image: Shutterstock

The memories of a cancer cell

A group of scientists at the Weizmann Institute of Science recently investigated what happens to cellular memory in cancer. Their findings illustrate how "memory loss" may affect the course of malignant diseases
Mouse liver tissue under the microscope. Signs of acute liver failure (left) disappeared after administration of a drug that blocks the control protein MYC

Involvement of intestinal bacteria and liver cells in acute liver failure

Weizmann Institute of Science scientists revealed the discovery and outlined a path for future treatment
The scarred surface near the North Pole of the Moon as captured by one of the cameras of NASA's LRO probe. The first step of the researchers was to decipher the two-dimensional images in an attempt to understand how many pits and depressions there are in these areas, what their possible depth is and what proportion of their surface is permanently shaded NASA /GSFC/ASU

The frozen side of the moon

A new study by Weizmann Institute of Science scientists and their research partners in the USA indicates that at least some of the water on the moon may be trapped in much more accessible places - in pits and small depressions.
A cell of Nicotiana benthamiana under a microscope. On the left: the intraplasmic reticulum (marked in green), in the center: the enzyme SOAP5 (marked in red) and on the right - a combined image revealing that SOAP5 is surprisingly found inside the intraplasmic reticulum

Foam over the spinach

In a new study, Weizmann Institute of Science scientists revealed the chain of biochemical reactions responsible for the production of saponins in plants, and discovered that it includes a surprising case of molecular "hijacking". The scientists even recorded an achievement in the field of synthetic biology: they restored the chain in its entirety through genetic engineering
As the word spread and panic gripped the public, the city officials ordered the killing of London's cats and dogs on the assumption that the fleas they carry were spreading the deadly bacteria. The assumption was not wrong - fleas do indeed carry the disease-causing bacteria - but the trustees of public health forgot an important factor in the equation: the rats. Photo: H. Zell, Wikimedia.

Mustache signature

  • No comments
When the NXF1 protein is in the cells properly (left), the RNA molecules (orange dots) of a particular single-exon gene are exported from the nucleus (marked in purple) into the cell fluid. When NXF1 is silenced (right), RNA molecules are mostly stuck in the nucleus

Export in the slow route

  • No comments
The "export" of RNA from the cell nucleus - a necessary process in the creation of proteins and the existence of life in a cell with a nucleus - was previously considered to be uniform and fast. In a new study, Weizmann Institute of Science scientists revealed that there are at least two pathways for RNA export, and that the cell can inhibit certain RNA molecules in the nucleus, while others go out into the cell fluid in the fast and familiar pathway
Strontium titanate at atomic resolution. split personality

Crystalline personality disorder

  • 2 תגובות
Science website logo
SEARCH