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The brain - depression and addictions

Brain during stress and without it. SN - the saliency network: reacts to significant events for a person, and when stressed expands in the cerebral cortex at the expense of the executive functions network ECN - the executive functions network: involved in attention, working memory, emotional regulation and social functioning and studies DMN - the default network: a system of brain areas that is mainly active in situations Rest in which the person is awake. Changes significantly after exposure to trauma and depression and anxiety

on anxiety and relaxation

Negative events in childhood and sleep problems make it difficult to recover from an acute stress disorder and thus increase the risk of a mental disorder
eye movements Illustration: depositphotos.com

See a world

A study examined the way in which different subjects - healthy, with depression or attention disorder - choose to look at the world
Smoking rehab. Illustration: depositphotos.com

at the top of their concerns

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Significant progress towards personalized medicine in the field of psychiatry, with the help of a helmet that induces electromagnetic stimulation of the brain.
An oligodendrocyte-type cell with many of its branches (in yellow) in a mouse brain section. Reacts to stress quite differently in males and females

Exposure to chronic stress activates different cells in the brains of females and males

From depression and anxiety to diabetes - health conditions resulting from chronic stress affect women and men differently. New study in mice maps at the single-cell level molecular differences in the stress response in the brains of females and males, and may pave the way for personalized treatments
Opioid and cannabinoid receptors are involved in pain sensation, mood, appetite and memory. Agonists are strong pain relievers: endorphin (red) and tetrahydrocannabinol (green). Illustration: depositphotos.com

New research reveals a brain component that regulates the urge to consume opiates

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Research from the Hebrew University reveals the identity of an area of ​​the brain that can moderate and balance the urge to consume the drug, and therefore may contribute to reducing addiction. The study provides a glimmer of hope that the ongoing battle with opioid addiction can be won
Microglial cells (in green) in the hippocampus region of the brain of an adult mouse, forming contact points with a new neuron (in red)

The biology of depression

Degeneration of the cells of the immune system in the brain may be the biological cause of depression, and there may be substances that can restore these cells - and be antidepressants
Depression and loneliness. Illustration: depositphotos.com

Interpretation enhances reality

Psychotherapy in which the therapist also offers interpretations of behavior is more helpful in reducing depression among patients who have difficulty managing relationships
drug addiction. Image: depositphotos.com

Discovery of Bar-Ilan University: Placental cells for natural addiction treatment

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Stem cells derived from the placenta are able to reach damaged tissues in the brains of drug addicts and initiate a rehabilitation process in them. The innovative treatment may solve one of the most difficult challenges in the field of detoxification: the difficulty of addicts to detach from the memory that brings them back again and again to the drug
How ketamine works: a schematic diagram of the new mechanism discovered in the study alongside the known mechanism. Ketamine molecule directly inhibits a certain type of receptors for the neurotransmitter glutamate (top left) and produces a chain reaction that leads to increased expression of potassium ion channels (KCNQ) in neurons of the glutamate system in the anterior hippocampus (right)

Crossing the canal: how does today's most promising molecule for the treatment of depression work?

Using advanced methods for genetic sequencing at the single cell level, Weizmann Institute of Science scientists reveal a new molecular mechanism of action of ketamine - and show that combining it with another drug may lead to improved performance and reduced side effects
Stress in old age. Illustration: depositphotos.com

A new study examines the impact of stressful situations and trauma on adults aged 65 and over

The researchers: "It is possible to characterize certain adults as having a high risk of increased deterioration due to the events they have experienced throughout their lives. Awareness must be raised about the link between stress and trauma and health decline in old age, and mechanisms must be built that will provide an adapted response, and help those adults deal with these consequences."
glial cells. Illustration: depositphotos.com

New discoveries about the structure and function of cells in the brain will lead to more effective drugs against depression

A group of researchers reveals for the first time the mechanism of action of electric shock therapy, the most effective procedure for the treatment of clinical depression, and subsequently developed a drug that mimics its mechanism of action and reduces symptoms of depression
wakefulness and sleep cycle. Illustration: depositphotos.com

You should sleep before an exam: lack of sleep sabotages the storage of new memories in the hippocampus

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Mice that suffered from a lack of sleep increased the activity of inhibitory neurons in the hippocampus, thereby disrupting the processing and storage of new memories.
Brain wave recording. Photo: depositphotos.com

Researchers at Ben-Gurion University present a new method for diagnosing neurological and psychiatric diseases

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The method, which is based on EEG patterns in abnormal electrical brain activity, can quickly diagnose and monitor pathologies in the blood vessels in the brain that are observed in conditions such as Alzheimer's disease, stroke, head injuries and psychiatric conditions
Radiation and depression. a href="https://depositphotos.com/">Illustration: depositphotos.com

The corona crisis resulted in a significant worsening of symptoms of anxiety and depression

The joint study by researchers from Tel Aviv University and Tel Hai College shows that in the midst of the second wave (October 2020) almost every third person in Israel (29%) suffers from high or very high anxiety symptoms
Psychotic disorders. Illustration: shutterstock

A blood test can predict who is likely to develop psychotic disorders

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The researchers analyzed blood samples taken from people who are at high clinical risk for psychosis. These people were followed for several years to see who developed a psychotic disorder and who did not.
A section of a mouse brain showing the expression of the ASL enzyme (in purple) in the brainstem region called the locus coeruleus. The laboratory of Prof. Ayelet Erez, Weizmann Institute

On the way to the brain, we stop at the liver

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autism. Illustration: shutterstock

The social life of nerve cells

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Dr. Takashi Kawashima and Dr. Mio Nonke. Photo: Weizmann Institute Spokesperson

The fish will play before us

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sleep. Illustration: shutterstock

Sleep on it!

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anxiety. Illustration: shutterstock

* Past emotional experiences affect the way anxiety-prone people perceive new experiences

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Fake marijuana, real crisis

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Insomnia. Photo: shutterstock

Israeli researchers have discovered a brain mechanism that is responsible for anxiety and hypersensitivity in people who do not sleep enough

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alcohol. Illustration: Taurus/Shutterstock

New compounds for the treatment of alcohol addiction

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Fetus in his mother's womb. Illustration: shutterstock

Researchers have discovered a fetal source of mood swings and bipolar disorder

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A person showing signs of depression. Illustration: shutterstock

Depression and anxiety predict a future increase in pain levels, but not the other way around

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